How do I use it?

Open the packaging, remove the silicone tip from the end, take out pen and inhale from the end with the hole. Breath in and out naturally. There is no button or anything else you need to do.

Take 10-20 puffs whenever desired. There is no upper-limit on the amount of B12 you can have in any given day.

20-30 puffs is approximately 500 mcg of B12 (>8,000% Daily Value).

When it runs out, throw it away or recycle it – you’ll know it’s out because no more vapor will come out and the LED will no longer light up.


Does it work?

The inhalation science of B12 dates back 60+ years. During that time, it has been shown that B12 inhalation can be orders of magnitude more efficient than oral supplementation, and completely non-toxic.


But is inhalation really that much better than taking pills?

A direct quote from an academic, peer-reviewed paper on the subject tackles this question:

“To further evaluate the efficacy of pulmonary absorption of the inhaled B-12 over and above the evidence afforded by the clinical and hematological response previously described, urinary excretion studies were performed… Upon oral administration of B-12 at dosages as high as 10,000 mcgm B-12 activity in urine has been shown to be less than 0.05 millimicrograms/ml. After inhalation of only 200 mcgm of B-12 in saline, B-12 activity in the urine reached the level of 0.26 millimicrograms/ml and following inhalation of approximately 500 mcgm of B-12 in a lactose powder B-12 activity in the urine rose to 0.134 millimicrograms /ml. Direct pulmonary instillation of 100 micrograms of crystalline vitamin B-12 by means of the bronchoscope resulted in a urinary excretion (9.76 millimicrograms/ml.) pattern equivalent to the intramuscular injection of 60-80 mcgm.”

F.J. Smith, R.W. Monto, J.W. Rebuck, “B12 Inhalation Therapy in Pernicious Anemia,” Trans Am. Clin. Climatol. Assoc. Vol. 64, p. 27 (1953).

These measurements imply that inhalation can be order(s) of magnitude more absorbent than pills.


Why is vitamin B12 so important?

According to the National Institute of Health:

“Vitamin B12 is a nutrient that helps keep the body’s nerve and blood cells healthy and helps make DNA, the genetic material in all cells. Vitamin B12 also helps prevent a type of anemia called megaloblastic anemia that makes people tired and weak.”

The UK Vegan Society, the Vegetarian Resource Group, and the Physicians Committee for Responsible Medicine, among others, recommend that vegans either consistently eat B12-fortified foods or take a daily or weekly B12 supplement to meet the recommended intake.

In other words, getting enough vitamin B12 is very important.


But I read on the Internet you can’t inhale vitamins, is this a scam?

A couple of our competitors have been rightly called-out for selling products that contain vitamins that can’t be effectively vaporized. However, vitamin B12 is an ideal candidate for vaporizing, and the inhalation science goes back a half century.

Those studies found that inhaling B12 was both safe and very effective.


Can I take too much B12?

According to WebMD: “Even at high doses, vitamin B-12 seems fairly safe. Experts have not found a specific dose of vitamin B-12 that’s dangerous. No tolerable upper intake levels have been set.”


How long will it last?

Each vaporizer is designed to last 2 weeks of daily use as directed. By industry standard, our atomizer has a rating of ‘800 puffs’ though no one we know has ever actually achieved 800 puffs. We estimate closer to 300 real world puffs.


How do I know when it’s out?

The LED light at the bottom of the vaporizer will stop lighting up, and no more vapor will be produced when inhaling.


What are the ingredients?

They are as simple and pure as it gets:

Vegetable Glycerin USP, Deionized Water, Organic Fruit Flavor Extract (Water, Organic Ethyl Alcohol, and Natural Flavors), Vitamin B12 (Cyanocobalamin)

We NEVER use: Nicotine, Tobacco, Cannabinoids, Diacetyl, or Acetyl Propionyl


What does it taste like? Does it have a flavor?

It is a light, smooth flavor. We have watermelon, mint, rainforest (fruit), peach,  pineapple, grape, blueberry and Strawberry.


Does our product contain Diacetyl or Acetyl Propionyl?

No. Our products do NOT contain Diacetyl, Acetyl Propionyl, Nicotine, Tobacco, or Cannabinoids.


Is it safe?

According to the existing research on B12 inhalation:

“This simple form of therapy is not only effective, but safe and economical.”

R.W. Monto & J.W. Rebuck, “Nasal Instillation and Inhalation of Crystalline Vitamin B12 in Pernicious Anemia,” AMA Arch Intern Med. Vol. 93, p. 219 (1954).

“There was no evidence of irritation at the time of inhalation. I personally examined the patients’ chests periodically, and I was not able to determine abnormal signs in the lungs.In addition to the clinical examination, we obtained periodic roentgenograms of the chest and they showed no change.”

“Inhalation of crystalline B-12 in physiological saline or lactose powder has, to do date, produced no objective or subjective evidence of toxicity or sensitivity at the pulmonary site.”

F.J. Smith, R.W. Monto, J.W. Rebuck, “B12 Inhalation Therapy in Pernicious Anemia,” Trans Am. Clin. Climatol. Assoc. Vol. 64, p. 27 (1953).

You should not use ESCOthebrand if you are sensitive to any of the ingredients, cobalt, or nickel.

It is also worth noting that the long-term effects of vaporizing, in general, are not fully understood.


How to verify how well Our Pens work for you?In order to verify its effectiveness for yourself, you can follow some simple steps below:

  1. Consult your Doctor. Buy vitamin B12 blood tests at your local Quest or Labcorp testing lab.
  2. Go without B12 supplementation for 1 week (get your Doctor’s permission first) to establish your baseline B12 levels.
  3. Get your first B12 blood test performed.
  4. Inhale 20-30 puffs of ESCOthebrand Pen.
  5. Wait 5 minutes.
  6. Get your second B12 blood test performed.
  7. Repeat 4-6 for as many days as you’d like.
  8. Plot the results on a chart and see how well it worked for you!


Does vitamin B12 really give me energy?

Low B12 levels are often associated with fatigue. Taking B12 in those cases can be very beneficial for energy, but what about everyone else? Many swear by B12 as an energy aid, it is a primary ingredient in products like 5-Hour-Energy, but the science is unclear that B12 can be used as an energy aid for people who are not low on B12 to begin with. Customers that have lower B12 levels are the ones that should see the most energy benefit from using our products. Others may not see much of a difference at all.


Can I order outside of the USA?

Yes, and shipping is an additional $15. International buyers are responsible for all import duties and delivery risk. We will not refund lost packages sent out of the United States.


Who shouldn’t use ESCOthebrand Pens?

Anyone with a sensitivity to any of the listed ingredients, cobalt, nickel, or vaporizing in general should NOT use these. Please consult your physician for any health-related questions.

Vegetable Glycerin USP, Deionized Water, Organic Fruit Flavor Extract (Water, Organic Ethyl Alcohol, Natural Flavors), and Vitamin B12 (Cyanocobalamin)


Is this a one-time purchase or a monthly purchase?

By default, all purchases are one-time only. However, if you wish to subscribe and save money through automatic monthly shipments, you can do so. We do not play cancellation games or use tricks to trap you into subscriptions. You can cancel at anytime and at no penalty.

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